Come meet BICCN members at these events

• Satellite Event. Responsible Conduct of Research Short Course. Friday, November 11, 2022, 1:00-5:30 pm, SDCC, Room 10. Anita Bandrowski (UCSD) and Satrajit Ghosh (MIT) presenting.  Link. 

• Satellite Event. Open resources for cell types and taxonomies with the Allen Brain Map.  Saturday, November 12, 2022, 7:30-10:30am, Marriott Marquis San Diego Marina, Pacific Ballroom 14-17.  Register!

• Social.  Tools, Tech & Theory: A BRAIN Initiative Alliance Social at the 2022 Society for Neuroscience Annual Meeting. The Allen Institute for Brain Science is a sponsor and participant in this Brain Initiative meeting. At this social, meet leading toolmakers supported by the BRAIN Initiative. Sunday, November 13, 6:30-9:30pm. Hilton Bayfront.

• Allen Institute Booth Session. BICCN applications and data portals for neuroanatomy and connectomics. Monday, Nov. 14, 11-12pm. Allen Institute Booth #1312.  Speakers: Rachel Dalley, Pooja Balaram, Zizhen Yao. Topics include:  Single cell reconstructions from slice and fMOST data and BIL data access; Molecular Probes Database to identify antibody targets and and light sheet imaging to visualize connectomics; introduction to the mouse whole brain cell type atlas and merfish dataset.

• NIF Booth Session. BICCN Data Archives and Resources.  Monday, Nov. 14, 1-2pm. NIF Booth #3314.  Speakers: Satrajit Ghosh and Yarik Halchenko (DANDI), Brock Wester (BossDB), Carol Thompson (AIBS), Anita Bandrowski (UCSD).  Topics include:  BRAIN Data Archives DANDI and BossDB; finding resources through the BICCN portal; Research Resource Identifiers.

• Allen Institute Booth Session. BICCN and Allen Brain Map applications enabling users to explore, visualize, and download multimodal datasets describing mammalian brain cell types. Tuesday, Nov. 15, 11-12pm. Allen Institute Booth #1312. Speakers: Patrick Ray, Raymond Sanchez, Jeremy Miller.  From Portals to Explorers: learn about gene expression and cell type phenotypes using the Transcriptomics Explorer and Cell Types Knowledge Explorer.

 

Special lecture

• Monday, November 14, 10:35-11:20am: Open Neuroscience and the Meaning of FAIR. Maryann Martone, UCSD. SDCC Ballroom 20.
• Monday, November 14, 12–1pm: Understanding Brain Cell Type Diversity. Hongkui Zeng, Allen Institute for Brain Science. Ballroom 20 and livestreamed.

Symposia, minisymposia, and nanosymposia

Sunday, November 13, 2022, 8:00-10:30 pm. Nanosymposium: Autism and Synapse Development. SDCC1.

• Presentation, 8:00-8:15am: L. Zhou, Properties of the synaptic modules in the developing human cortex. #100.01

Monday, November 14, 2022, 9:30am - 12pm. Nanosymposium: On Neural Connectomics. SDCC25.

• Presentation, 1:00-1:15pm: Pooja Balaram, A pipeline for high resolution axonal connectomics in nonhuman primates and humans.

Wednesday, November 16, 2022, 8:00-10:15 am. Nanosymposium: Genomics and Transcriptomics in Health and Disease. SDCC 23.

• Presentation, 9:00-9:15am: Rongxin Fang. Spatially resolved single-cell transcriptomics reveals conservation and divergence of the cellular organization in human and mouse cortices. #598.05

Wednesday, November 16, 2022, 1:00-2:45 pm. Nanosymposium: Epigenomic and Transcriptomic Cell Type Atlas of the Whole Mouse Brain. SDCC 1.

• Presentation, 1:00-1:15pm: Michael Kunst, A whole-brain mouse spatial transcriptomics atlas. #684.01
• Presentation, 1:15-1:30pm: Meng Zhang, A molecularly defined and spatially resolved cell atlas of the whole mouse brain.  #684.02
• Presentation, 1:30-1:45pm: J. Langlieb, A spatial and single-cell transcriptional atlas of the adult mouse brain.  #684.03.
• Presentation, 1:45-2:00pm: Zizhen Yao, A whole mouse brain transcriptomic cell type atlas. #684.04
• Presentation: 2:00-2:15pm: J. Zhou, Brain-wide Correspondence Between Neuronal Epigenomics and Long-Distance Projections. #684.05
• Presentation, 2:15-2:30pm: S. Zu, Comprehensive single-cell analysis of chromatin accessibility in the adult mouse brain. #684.06.
• Presentation: 2:30-2:45 pm: Hanqing Liu, Dna methylome and 3d chromatin landscape of cell types across the mouse brain.  #684.07

Saturday, Nov. 12

Poster Session: 031 - Comparative Cellular and Molecular Mechanisms. SDCC Halls B-H

• Marmosets have birth siblings' microglia. Poster. Sat., Nov. 12., 2:00-3:00 pm #031.06 / B26.
• Comprehensive analysis of single-cell chromatin accessibility in the human brain. Poster. Sat., Nov. 12., 2:00-3:00 pm. #031.10 / B30.
• Areal specializations in L5 extratelencephalic-projecting neuron morpho-electric and transcriptomic properties in the primate neocortex. Poster. Sat., Nov. 12, 2:00-3:00 pm. #031.11 / B31.
• Morphoelectric and transcriptomic divergence of the layer 1 interneuron repertoire in human versus mouse neocortex. Poster. Sat., Nov. 12, 2:00-3:00 pm. #031.14 / B34.
• Single nucleus methylome and 3D chromatin heterogeneity reveals cell-type identity, spatial location and regulatory genome complexity in the human brain. Poster. Sat., Nov. 12., 3:00-4:00 pm. #031.15 / B35.
• Cross-species taxonomies of primate basal ganglia cell types defined by single nucleus RNA-sequencing. Poster. Sat. Nov. 12., 4:00-5:00 pm.  #031.16 / B36.
• Transcriptomic diversity of cell types across the adult human brain. Poster. Sat., Nov. 12., 1:00 PM - 2:00 pm. #031.17 / B37.
• Signature morpho-electric properties of GABAergic interneuron subclasses and types in the human neocortex. Poster. Sat., Nov. 12, 3:00-4:00 pm. #031.19 / B39.
• A marmoset brain cell atlas reveals effects of local context on neurons. Poster. Sat., Nov. 12., 4:00- 5:00 pm. #031.20 / B40. 
• An integrative single-cell genomics analysis of Alzheimer’s disease identifies cellular state alterations and neuronal vulnerabilities. Poster. Sat., Nov. 12, 2:00-3:00 pm. #031.22 / B42.
• Cellular and molecular specialization of functional areas in human neocortex. Poster. Sat., Nov. 12, 3:00-4:00 pm. #031.23 / B43.
• Inter-individual genomic and transcriptomic variation in human cortical cell type. Poster. Sat., Nov. 12, 2:00-3:00pm. #031.26 / B46. 

Poster Session 083 - Single Cell profiling Technique in Health and Disease. SDCC Halls B-H.

• Multiple modality classification of long-ragne projecting, glutamatergic neurons in mouse visual cortex. Poster. Sat., Nov. 12., 4:00-5:00 pm. #083.20 / VV34.
• Modular and hierarchical cell type organization of cortical areas revealed by in situ sequencing. Poster. Sat., Nov. 12, 2:00-3:00pm. #083.18 / VV32.

Sunday, Nov. 13

Poster Session 162 - Bioinformatics and Systems Biology. SDCC Halls B-H.

 

• DANDI: An archive and collaboration space for cellular neurophysiology projects. Poster. Sun., Nov. 13, 8:00-9:00am. #162.05 / XX2.
• The cellxgene suite is an online analytical platform and the largest repository of standardized single-cell data. Poster. Sun., Nov. 13, 11:00am-12:00pm. #162.04 / XX1.

Poster Session 245 - Tools and Resources for Data Standardization and Data Sharing.  SDCC Halls B-H.

• Ontologies to support BRAIN Initiative Cell Census Network (BICCN) data and future expansion. Poster. Sun., Nov. 13., 4:00-5:00pm. #245.04 / XX46.
• A Guide to Five years of Data from the BRAIN Initiative Cell Census Network (BICCN). Poster. Sun., Nov. 13., 1:00-2:00 pm. #245.05 / XX47.

Other Poster Sessions

• Brain-wide circuit representations of sensory and behavioral responses to olfactory stimuli in adult Drosophila. Poster. Sun., Nov. 13., 4:00-5:00 pm. #209.04 / N9.
• EPIC-Clear: enzyme powered IHC-compatible clearing for whole organs and whole animals. Poster. Sun., Nov. 13., 2:00-3:00 pm #242.02 / WW45.
• Histological validation of human post mortem amygdala DTI. Poster. Sun., Nov. 13., 11:00-12:00 pm. #164.12 / XX37.
• Effective preservation of biomolecules in frozen human brain tissues for 3D spatial multi-omic analysis. Poster. Sun., Nov. 13., 9:00-10:00 am #161.02 / WW43.

Monday, Nov. 14

Poster Session 411 - Light and Electron Microscopy Techniques. SDCC Halls B-H.

• A parallelly distributed microscope and software system for scalable high-throughput multispectral 3D imaging. Poster. Mon., Nov. 14, 3:00-4:00pm. #411.03 / YY54.
• High-throughput light-sheet microscopy imaging: a custom hardware setup and a software stack for large-scale brain tissue reconstruction. Poster. Mon.,  Nov. 14., 4:00-5:00 pm #411.04 / YY55.
• 3d molecular phenotyping of human brain samples with light-sheet. Poster. Mon.,  Nov. 14., 3:00-4:00 pm #411.11 / YY62.
• High-throughput airy beam light-sheet tomography of brain-wide imaging at single-cell resolution. Poster. Mon., Nov. 14, Web Only. #411.12.

• A common coordinate framework for quantitative cell census in developing mouse brains. Poster. Mon.,  Nov. 14., 3:00-4:00 pm #359.09 / D11.
• Brain-wide cellular resolution mapping of GABAergic cells and microglia unveils spatially distinct developmental patterns in the early postnatal mouse brain. Poster. Mon.,  Nov. 14., 2:00-3:00 pm #350.02 / A2.

Tuesday, Nov. 15

Poster Session 498 - Computational Tools and Other Resources: Microscopy and Imaging

• The Brain Image Library- a brain microscopy resource. Poster. Tue., Nov. 15., 11:00-12:00pm. #498.04 / YY59.
• Nyquist Sampling Rate for Projection Neuron Reconstruction. Poster. Tue., Nov. 15., 9:00-10:00am. #498.10 / YY65.
• A Universal Conversion Service of Digital Reconstructions into the SWC Standard Community Format.  Poster. Tue., Nov. 15., 10:00-11:00am. #498.11 / YY66.
• Neuromorpho.org at sweet 16: sharing neural reconstructions in the big data era. Poster. Tue.,  Nov. 15., 11:00-12:00 pm #498.12 / YY67.
• Petabyte-scale image visualization and annotation on the Brain Image Library with nTracer2. Poster. Tue.,  Nov. 15., 8:00-9:00 am #498.25
• An automated pipeline for mouse whole-brain CCF registration. Poster. Tue.,  Nov. 15., 9:00-10:00 am #498.26

Poster Session 576 - Visualizing Nerual Connectivity with High Resolution. SDCC Halls B-H.

• Towards routine reconstruction of C. elegans connectomes, cell states, and cell types, through optimized expansion microscopy. Poster. Tue.,  Nov. 15., 1:00-5:00 pm #576.01 / XX50.
• Ultrastructural membrane expansion microscopy (umExM) for electron microscopy-like imaging of brain circuits. Poster. Tue.,  Nov. 15., 1:00-5:00 pm #576.02 / XX51.
• Multiplexed Expansion Revealing (multi-ExR): Development and Application to Mapping Nanostructures in Healthy and Alzheimer's Disease Brains. Poster. Tue.,  Nov. 15., 1:00-5:00 pm #576.04 / XX53.
• Expansion Microscopy of Liquid Biopsies. Poster. Tue.,  Nov. 15., 1:00-5:00 pm #576.05 / XX54.
• Next-generation expansion sequencing. Poster. Tue.,  Nov. 15., 1:00-5:00 pm #576.07 / XX56.
• Scalable sets of brainbow-like protein barcodes for scalable expansion microscopy-based neural morphology measurement and connectomics. Poster. Tue.,  Nov. 15., 1:00-5:00 pm #576.09 / XX58.
• 16-fold expansion microscopy (16exm) enables single-shot ultrahigh resolution imaging on conventional microscopes. Poster. Tue.,  Nov. 15., 1:00-5:00 pm #576.11 / XX60.

Wednesday, Nov. 16

• Hippocampome.org v2.0 - a knowledge base enabling neuron-type specific spiking neural network simulations of hippocampal circuits. Poster. Wed.,  Nov. 16., 3:00-4:00 pm #742.11.