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R24 - Wester 1R24MH114785-01A1

Boss: A cloud-based data archive for electron microscopy and x-ray microtomography

Brain Observatory Storage Service and Database (BossDB) is a volumetric database for 3D and 4D neuroimaging data. BossDB focuses primarily on storing volumetric Electron Microscopy (EM) and X-Ray Microtomography (XRM) datasets generated as a part of the BRAIN Initiative. BossDB stores high resolution, multi-channel image data with registered segmentations, annotations and meshes, and connects to a number of community resources for data access and data visualization. BossDB also stores connectomics datasets and contains a number of software tools and interfaces for querying and searching connectomes.

Volumetric high-resolution neuroimaging data enables structural, neuroanatomical, and microscale connectomics based research, which are instrumental to fulfilling the BRAIN Initiative goal of understanding neural circuits and neural connectivity.

BossDB is operated by the Research and Exploratory Development Department of Johns Hopkins University Applied Physics Laboratory.

Project Leadership

Brock Wester, Ph.D. (Principal Investigator, contact)

Assistant Program Manager, Principal Staff, Johns Hopkins University Applied Physics Laboratory
Vice Chair, Applied Biomedical Engineering Program, Johns Hopkins University
Laurel, MD, USA

https://ep.jhu.edu/faculty/brock-wester/
https://www.jhuapl.edu/OurWork/GetPersonBio/Wester_Brock_984

 

Will Gray-Roncal, Ph.D. (Key Personnel)

Group Supervisor, Principal Staff, Johns Hopkins University Applied Physics Laboratory
Assistant Research Professor, Computer Science and Education Johns Hopkins University
Laurel, MD, USA

https://ep.jhu.edu/faculty/william-gray-roncal/

 

Robert Hider Jr. (Key Personnel)

BossDB Collaborator, Technical Lead
Senior Professional Staff, Senior Software Engineer, Johns Hopkins University Applied Physics Laboratory
Laurel, MD, USA

Project Data Types

  • Electron Microscopy and X-Ray Microtomography volumetric image data

  • BossDB can ingest a variety of image data types and encodings, and can provide image, object, and segmentation data in multiple formats (e.g., PNG, JPG, TIFF, numpy array, etc.)  through our application programming interface (API).

     

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