Explore the growing set of cutting-edge scientific packages developed as major outcomes of the BICCN's collaborative efforts. Discover how these powerful datasets are revolutionizing our understanding of the brain and its cell types.
Science, Science Advances, and Science Translational Medicine - October 13, 2023
With over 100 billion neurons in the human brain, understanding the cellular diversity and differences between human and non-human primate (NHP) brain will lay a key foundation for future brain and disease research. This curated collection of studies is dedicated to deciphering the nuanced gene expression by species and age and functional and anatomical properties that delineate these cell types.
Nature - October 6, 2021
A multimodal cell census and atlas of the mammalian primary motor cortex (MOp or M1) was achieved as the initial product of the BRAIN Initiative Cell Census Network (BICCN). Coordinated large-scale analyses of single-cell transcriptomes, chromatin accessibility, DNA methylomes, spatially resolved single-cell transcriptomes, morphological and electrophysiological properties, and cellular resolution input-output mapping, integrated through cross-modal computational analysis.